"Every perception is to some degree an act of creation, and every act of memory is to some degree an act of imagination."
-- Gerald Edelman, Second Nature: Brain Science and Human Knowledge
6 On the role of cognitive science in the design of systems to augment cognition8 On the role of cognitive science in the design of systems to augment cognitionOn the role of cognitive science in the design of systems to augment cognitionAugmenting Long-term Memory2020-09-24Journal
But what are they supposed to do? Wait 50 or 100 years, until those answers are in? Give up design, and become memory scientists for the next 30 years, so they can give properly “scientific” answers to all the questions they need answered in the design of their systems?
This isn't the way design works, nor the way it should work.
If designers waited until all the evidence was in, no-one would ever design anything. In practice, what you want is bold, imaginative design, exploring many ideas, but inspired and informed (and not too constrained) by what is known scientifically. Ideally, alongside this there would be a much slower feedback loop, whereby design choices would suggest questions about memory, which would lead to new scientific experiments, and thence to an improved understanding of memory, which would in turn suggest new avenues for design.